Two seniors who have mesothelioma cancer are riding bikes.

Definition of Mesothelioma: A rare, aggressive form of cancer that attacks the tissue lining of internal organs. This protective tissue lining is known as the mesothelium. While the main cause of various cancers is vaguely understood, this form of cancer is a man-caused cancer which is directly associated to a person being exposed to asbestos. Once tiny asbestos fibers have entered the body via esophageal or tracheal pathways, they will become lodged into the protective tissue lining mentioned above.  This lodging disrupts natural cell development, which promotes the growth of abnormal cells, which ultimately leads to either asbestosis or some form of mesothelioma cancer.

The mesothelium consists of two layers:

  • The inner layer of the mesothelium wraps directly around major organs like the lungs, abdomen, and heart.  This is the first layer of protection.
  • The outer mesothelium layer forms a sac that surrounds the inner layer; mesothelioma grows in between or on these two linings.

There are three known and medically accepted types of mesothelioma with the probability of there being a fourth type. The reason for the “probability” is because it is so rare that there isn’t enough data history to rule it as a direct connection with cancer of the mesothelium. From here on out, we’re going to assume there are four types of mesothelioma as there is important information to learn about all four.

Last Modified: Mar 29, 2017 @ 6:39 pm

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Show Sources

Resources:

  1. Brigham and Women’s Hospital – International Mesothelioma Program
    (http://www.brighamandwomens.org/Departments_and_Services/surgery/services/thoracicsurgery/services/meso
  2. Wagner, J.C., Sleggs, C.A., and Marchand, Paul. “Diffuse Pleural Mesothelioma and Asbestos Exposure in the North Western Cape Province.” Department of Thoracic Surgery: University of The Witswatersrand. Johannesburg, South Africa. 1960.
  3. National Cancer Institute – A Malignant Asbestos-related cancer  (http://www.cancer.gov/cancertopics/types/malignantmesothelioma)
  4. National Cancer Institute. (2009, May 1). Asbestos exposure and cancer risk. http://www.cancer.gov/about-cancer/causes-prevention/risk/substances/asbestos/asbestos-fact-sheet
  5. Straif, K. (2011, March 17). Update of the Scientific Evidence on Asbestos and Cancer. Retrieved from http://www.who.int/phe/news/events/international_conference/Session2_DrStraif.pdf
  6. Dodson, R. and Hammar, S. (2011). Asbestos: Risk Assessment, Epidemiology, and Health Effects. Taylor & Francis: Boca Raton.
  7. Castleman, B. (2005). Asbestos: Medical and Legal Aspects. Aspen Publishers: New York.
  8. Mesothelioma: Causes and Symptoms. WebMD. Retrieved From: http://www.webmd.com/lung/mesothelioma-causes-and-symptoms. Retrieved 3/17/16.
  9. Mesothelioma Symptoms. Mayo Clinic. Retrieved From: http://www.mayoclinic.com/health/mesothelioma/DS00779/DSECTION=symptoms. Retrieved on 3/17/16.
  10. Webster, P. (2005). White Dust Black Death. Trafford: Canada.
  11. Robinson, B., Musk, A., Lake, R. (2005). Malignant Mesothelioma. The Lancet; 366(9483): 397-408.
  12. Yang, H, Rivera, Z, Jube, S, et al. (2010, July 13). Programmed necrosis induced by asbestos in human mesothelial cells causes high-mobility group box 1 protein release and resultant inflammation. PNAS; 107(28): 12611-12616. Retrieved from http://www.pnas.org/content/107/28/12611.full.pdf
  13. Carbone, M, Yang, H. (2012). Molecular pathways: Targeting mechanisms of asbestos and erionite carcinogenesis in mesothelioma. Clin Cancer Res; 18. Retrieved from https://clincancerres.aacrjournals.org/content/18/3/598.full
  14. Hodgson, JT, Darnton, A. (2000). The qualitative risk of mesothelioma and lung cancer in relation to asbestos exposure. Ann Occup Hyg; 44: 565-601. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/11108782
  15. Blum, D. (2016, February 9). In Nevada, a controversy in the wind. Retrieved from http://www.nytimes.com/2015/02/10/science/a-controversy-in-the-wind.html?_r=0

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